Driving directions from Reeds Spring, MO to Durham, NC

Driving directions between Reeds Spring, MO and Durham, NC. Estimated driving time is , with an average speed of about 48 miles per hour. If you want more accurate directions from your actual position or to a certain place or street, you may search street or place names directly.

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Find the directions listed below in order to go from Reeds Spring, MO to Durham, NC by car. You can click each direction to see them in the map.

US 60, I 40

975.2 mi16 hours 3 mins

Head northwest on Spring Street 100 feet
Continue onto Main Street (MO 265) 0.4 mi
Turn right onto 248 1.4 mi
Turn left onto MO 13 0.8 mi
Continue onto US Highway 160 (US 160) 4.6 mi
Continue onto US 160 22.5 mi
Take the ramp towards US 60 East: Rogersville 0.3 mi
Merge left onto James River Freeway (US 60) 85.7 mi
Keep left towards US 60 East: Mountain View 69.5 mi
Continue onto US 60 25.5 mi
Continue onto North Westwood Boulevard (US 60 Business) 800 feet
Make a slight left 300 feet
Turn left onto Route W (MO W) 800 feet
Take the ramp on the right 0.2 mi
Merge left onto US 60 72.5 mi
Continue onto Cairo I-57 Bridge (I 57 N) 1.7 mi
Take the ramp towards US 51 south: Cairo 200 feet
Continue straight 0.5 mi
Turn left onto US 51 9.7 mi
Turn left onto 4th Street (US 60) 0.2 mi
Continue onto Lee Street (US 60) 700 feet
Continue onto North 6th Street (US 60) 5.9 mi
Continue onto South 4th Street (US 60) 0.2 mi
Turn right onto Broadway (US 60) 0.6 mi
Continue onto Paducah Road (US 60) 3.2 mi
Continue onto West Kentucky Avenue (US 60) 0.5 mi
Continue onto Paducah Rd (US 60) 6.1 mi
Continue onto Old Hinkleville Rd (US 60) 10.6 mi
Take the ramp towards Nashville 0.2 mi
Merge left onto Interstate 24 (I 24 E) 133.0 mi
Keep right towards I 24 East: Nashville 2.3 mi
Keep left towards I 24 East: Chattanooga 2.8 mi
Keep left towards I 40 East: Knoxville 210.2 mi
Keep right towards I 40 East: Asheville 217.8 mi
Keep right onto I 40 31.8 mi
Merge right onto I 40 1.8 mi
Keep left onto I 40 6.1 mi
Merge left onto I 40 30.6 mi
Keep left towards I 85 North: Durham 9.4 mi
Keep right towards NC 147 South: Downtown Durham 5.2 mi
Take the ramp towards Mangum Street 500 feet
Go straight onto Morehead Avenue 900 feet
Turn left onto Roxboro Road (US 15 Business) 0.4 mi
Turn left onto East Main Street 100 feet
You have arrived at your destination, on the right

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