Driving directions from Santa Fe, TX to Winston Salem, NC

Driving directions between Santa Fe, TX and Winston Salem, NC. Estimated driving time is , with an average speed of about 48 miles per hour. If you want more accurate directions from your actual position or to a certain place or street, you may search street or place names directly.

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Find the directions listed below in order to go from Santa Fe, TX to Winston Salem, NC by car. You can click each direction to see them in the map.

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