Driving directions from Santa Fe, TX to Winston Salem, NC

Driving directions between Santa Fe, TX and Winston Salem, NC. Estimated driving time is , with an average speed of about 48 miles per hour. If you want more accurate directions from your actual position or to a certain place or street, you may search street or place names directly.

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Find the directions listed below in order to go from Santa Fe, TX to Winston Salem, NC by car. You can click each direction to see them in the map.

I 10, I 85 $north

1,121.1 mi17 hours 16 mins

Head northwest on Highway 6 (TX 6) 0.4 mi
Turn right onto Farm-to-Market Road 1764 (FM 1764) 1.6 mi
Turn left onto 16th Street (FM 646) 3.5 mi
Turn right onto FM 517 3.3 mi
Make a slight left onto Dickinson Avenue (FM 1266) 2.6 mi
Turn right onto League City Parkway (TX 96) 2.8 mi
Turn left onto TX 146 19.7 mi
Merge right onto Baytown Loop (TX 146) 0.9 mi
Go straight onto Ferry Road (TX 146) 4.5 mi
Turn right onto East Freeway Frontage Road 900 feet
Take the ramp on the left 0.2 mi
Merge left onto I 10 29.9 mi
Keep left onto I 10 211.7 mi
Take the ramp on the left 0.8 mi
Continue onto I 12 84.4 mi
Keep left at the fork 0.4 mi
Keep left towards I 10: Bay Saint Louis 0.7 mi
Merge left onto I 10 102.5 mi
Take the ramp on the left towards I 65 North: Montgomery 0.6 mi
Continue onto I 65 N 170.5 mi
Take exit 171 towards 85: Atlanta 0.3 mi
Continue onto I 85 N 164.3 mi
Keep left towards I 85 North: Greenville 163.3 mi
Keep left onto I 85 N 120.7 mi
Continue onto I 85 0.6 mi
Continue onto I 85 N 3.8 mi
Keep right towards I 85 Business North: Lexington 4.1 mi
Keep left onto US 52 N 21.6 mi
Take the ramp towards I 40 Business West 900 feet
Merge left onto I 40 Business W 0.5 mi
Take the ramp towards South Main Street 900 feet
Turn right onto South Main Street 0.4 mi
You have arrived at your destination

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